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Periostat: An Effective Treatment for Chronic Gum Disease

Periostat is very small (20mg) dose of Doxycycline. It is a prescription pill that is taken morning and night for at least three months.

Is it ok to take an antibiotic for that long?

Yes it is ok. Because of the low dose, this medication doesn't kill bacteria. It decreases enzymes...

When you have gum disease your body responds by becoming inflamed.

Inflammation is the result of your body's effort to fix the problem.

As inflammation becomes chronic. Your body's response is an incease in enzymes.

The enzymes are meant to destroy bacteria but some of them end up destroying your tissue and bone that support your teeth.

This prescription medication slows your inflammatory response by decreasing the enzyme collagenase in patients with gum disease.

Studies have shown more improvement in gum pockets when taken after dental scaling and root planning compared to patients who had scaling and root planning alone.

Periostat is not recommended for:

  • children under age 8
  • pregnant or nursing women
  • anyone who is allergic to any tetracycline antibiotic


Should be taken:

  • after dental scaling and root planning
  • twice a day about 12 hours apart
  • close to meal times, one hour prior or two hours after a meal is ideal
  • With a full glass of water
  • 30 minutes before lying down

If your stomach gets upset, try taking it with some food but avoid taking it with milk or anything containing calcium.

Other brand names:

Adoxa, Alodox, Avidoxy, Doryx, Monodox, Oracea, Oraxyl, Vibramycin, Vibramycin Calcium, Vibramycin Monohydrate and Vibra-Tabs.

Periodontal Treatment

Side effects:

Because of the very low dose, side effects are rare.

My opinion:

I like periostat and recommend it for moderate to advanced gum disease. It is especially helpful for clients who smoke and are resistant to other methods.

Even though it is a very low dose it's best to take it for as short a time as possible. Three-six months is ideal.

Every situation is different and this medication may not work in every case. It's important to consult your dentist or dental hygienist.

Source: Rxlist.com

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